Welcome to the van Pijkeren Laboratory!
We work at the interface of industry and medicine. While we have completed projects with various lactic acid bacteria, most of our research focuses on Limosilactobacillus reuteri, until recently known as Lactobacillus reuteri. L. reuteri is an important gut symbiont, and select strains have demonstrated health-promoting, i.e., probiotic, properties. The ultimate goal of our research program is to understand probiotic mechanisms towards the development of next-generation probiotics.
For many years, we have invested in developing genetic tools for use in L. reuteri and other lactic acid bacteria. As a consequence, our laboratory is at the forefront of lactic acid bacteria genome editing. These genome editing tools place us in the exciting position to pursue research in the following areas:
(1) to unravel the molecular underpinnings by which probiotic bacteria interact with the vertebrate host;
(2) to unravel the tripartite interplay between diet, a probiotic, and its bacteriophages;
(3) to develop probiotic bacteria as therapeutic delivery vehicles.
We’re grateful for our current and past funding, which, combined with great collaborators, made it possible to build a dynamic team of staff and students to drive our research.
If you are interested in learning more about our work, please don’t hesitate to contact us.
Finally, we took the plunge! The van Pijkeren laboratory is on Twitter. We hope to connect with many colleagues in the field, share interesting articles and tweets, and -of course- share our latest news and …May 25, 2017
The Van Pijkeren Laboratory is featured in several news articles that were recently published. MIT Technology Review published the article Edible CRISPR could replace antibiotics. Around the same time, the article Antibiotic alternatives, delivered by friendly microbes appeared …April 21, 2017
Looking back at 2016, it has been an exciting year, no doubt! For starters, we had our website launched to showcase our work! We are very proud of the final product, and we will continue …December 29, 2016
We’re very excited to have a new website! Check it out to meet the members of the van Pijkeren Laboratory, and to learn more about our research. We hope to keep you up to …September 13, 2016