PUBLICATIONS
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- González-Delgado A, Bonillo-Lopez L, Johnson MS, Knödlseder N, Ko CC, Lekbach Y, Oh JH, Selvakumar H, Wold MC, Yu Z, Aragón V, Gralnick JA, Güell M, Hatfull GF, Keitz BK, Koskella B, Mutalik VK, van Pijkeren JP, Shipman SL. Genome editing of phylogenetically distinct bacteria using portable retron-mediated recombineering. bioRxiv [Preprint]. 2025. PMID: 40667245; PMCID: PMC12262390.
- Zeng M, Oh JH, van Pijkeren JP, Pan X. Synthesis of potential prebiotic oligosaccharides with diverse glycosidic linkages from corn stover via simultaneous hydrolysis and glycosylation. Bioresour Technol. 2025 Aug;429:132486. Epub 2025 Apr 12. PMID: 40228723.
- Archer D, Pérez-Muñoz ME, Tollenaar S, Veniamin S, Hotte N, Cheng CC, Nieves K, Oh JH, Morceli L, Muncner S, Barreda DR, Krishnamoorthy G, Power C, van Pijkeren JP, Walter J. A secondary metabolite of Limosilactobacillusreuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis. Cell Rep. 2025 Mar 25;44(3):115321. Epub 2025 Feb 21. PMID: 39985770.
- She F, Anderson BW, Khana DB, Zhang S, Steinchen W, Fung DK, Lesser NG, Lucas LN, Stevenson DM, Astmann TJ, Bange G, van Pijkeren J-P, Amador-Noguez D, Wang JD. Allosteric regulation of pyruvate kinase enables efficient and robust gluconeogenesis by preventing metabolic conflicts and carbon overflow. mSystems. 2025 Feb 18;10(2):e0113124. Epub 2025 Jan 28. PMID: 39873491; PMCID: PMC11834443.
- Alexander LM, Khalid S, Gallego-Lopez GM, Astmann TJ, Oh J-H, Heggen M, Huss P, Fisher R, Mukherjee A, Raman S, Choi IY, Smith MN, Rogers CJ, Epperly MW, Knoll LJ, Greenberger JS, van Pijkeren J-P. Development of a Limosilactobacillus reuteri therapeutic delivery platform with reduced colonization potential. Appl Environ Microbiol. 2024 Nov 20;90(11):e0031224. Epub 2024 Oct 31. PMID: 39480094; PMCID: PMC11577788.
- Hamade DF, Epperly MW, Fisher R, Hou W, Shields D, van Pijkeren JP, Leibowitz BJ, Coffman LG, Wang H, Huq MS, Huang Z, Rogers CJ, Vlad AM, Greenberger JS, Mukherjee A. Genetically Engineered Probiotic Limosilactobacillus reuteri Releasing IL-22 (LR-IL-22) Modifies the Tumor Microenvironment, Enabling Irradiation in Ovarian Cancer. Cancers (Basel). 2024 Jan 23;16(3):474. PMID: 38339228; PMCID: PMC10854600.
- Zeng M, Oh JH, van Pijkeren JP, Pan X. Selective utilization of gluco-oligosaccharides by lactobacilli: A mechanism study revealing the impact of glycosidic linkages and degree of polymerization on their utilization. J Food Sci. 2024 Jan;89(1):523-539. doi: 10.1111/1750-3841.16851. Epub 2023 Nov 27. PMID: 38010727.
- Choi IY, Oh J-H, Wang Z, van Pijkeren J-P. Bioluminescent monitoring of recombinant lactic acid bacteria and their products. mBio. 2023 Oct 31;14(5):e0119723. Epub 2023 Sep 5. PMID: 37668408; PMCID: PMC10653940.
- Liu Y, Armbrister SA, Okeugo B, Mills TW, Daniel RC, Oh JH, van Pijkeren JP, Park ES, Saleh ZM, Lahiri S, Roos S, Rhoads J. Probiotic-Derived Ecto-5′-Nucleotidase Produces Anti-Inflammatory Adenosine Metabolites in Treg-Deficient Scurfy Mice. Probiotics Antimicrob Proteins. 2023 Aug;15(4):1001-1013. Epub 2023 May 13. PMID: 37178405; PMCID: PMC10926147.
- Hamade DF, Epperly MW, Fisher R, Hou W, Shields D, van Pijkeren JP, Mukherjee A, Yu J, Leibowitz BJ, Vlad AM, Coffman L, Wang H, Huq MS, Huang Z, Rogers CJ, Greenberger JS. Release of Interferon-β (IFN-β) from Probiotic Limosilactobacillus reuteri-IFN-β (LR-IFN-β) Mitigates Gastrointestinal Acute Radiation Syndrome (GI-ARS) following Whole Abdominal Irradiation. Cancers (Basel). 2023 Mar 8;15(6):1670. PMID: 36980556; PMCID: PMC10046795.
Recent Posts
Morgan named Deibel Fellow
Morgan has been named the 2026 recipient of the Robert H. and Carol L. Deibel Distinguished Graduate Fellowship in Probiotic Research! This prestigious FRI fellowship offers a generous stipend and research funds. Congratulations to Morgan!
May 14, 2026JP named director of FRI!
We are excited to announce that JP is now the director of the Food Research Institute (FRI)! The FRI is a leader in identifying and resolving food safety issues to meet community, government and industry …
March 2, 2026VPL at the GRC
In Young, Jeehwan, Mark, and Morgan were all selected as speakers at the 2025 Gordon Research Conference and Seminar Lactic Acid Bacteria Biology, Symbioses and Applications. A massive thank you to the co-chairs- especially JP- …
July 19, 2025A probiotic with reduced colonization potential
Congratulations to Laura, Saima, Theresa, Jee-Hwan, Mark, In Young , and Morgan for their work published in AEM! This paper characterized our lab’s creation of the LR6475 Nonuple strain, a mutant with nine genes encoding …
November 3, 2024mBio featured image!
Congratulations to In Young, Jeehwan, and Zhiying for their research published recently in mBio. Their work was selected for the featured image of the edition! “A cartoon of glowing bacteria passing through the gastrointestinal tract. …
December 1, 2023